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Symbol
Name
ID
Fshr
follicle stimulating hormone receptor
MGI:95583
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Increased circulating gonadotropin level
Decreased serum estradiol
Delayed puberty
Disease(s) Associated with FSHR
46 XX gonadal dysgenesis
ovarian dysgenesis 1

Mouse Phenotypes
ovary hemorrhage
increased granulosa cell proliferation
abnormal adrenal gland morphology
increased gonadotroph cell number
increased thyrotroph cell number
adenohypophysis hyperplasia
increased pituitary gland weight
pituitary gland hyperplasia
abnormal mammary gland morphology
decreased seminal vesicle weight
small seminal vesicle
abnormal endometrial gland morphology
enlarged endometrial glands
abnormal ovary morphology
absent corpus luteum
abnormal granulosa cell morphology
absent mature ovarian follicles
abnormal ovarian follicle number
decreased primary ovarian follicle number
absent ovarian follicles
abnormal ovarian folliculogenesis
impaired ovarian folliculogenesis
increased follicle recruitment
polyovular ovarian follicle
decreased ovary weight
small ovary
ovary atrophy
ovary cyst
abnormal seminiferous tubule morphology
abnormal seminiferous tubule epithelium morphology
decreased Sertoli cell number
small seminiferous tubules
abnormal testis development
abnormal testis size
decreased testis weight
small testis
increased ovary tumor incidence
increased ovarian carcinoma incidence
increased ovarian teratoma incidence
increased prolactinoma incidence
abnormal ovary physiology
decreased ovary secretion
abnormal testes secretion
Availability Mouse Genotype
Fshrtm1Hht/Fshrtm1Hht
Fshrtm1Mha/Fshrtm1Mha
Fshrtm1Saco/Fshrtm1Saco
Fshrtm1Hht/Fshr+
Fshrtm1Saco/Fshr+
Tg(AMH-Fshr)27Hht/0
Tg(AMH-Fshr*D580H)#Hht/0
Tg(AMH-Fshr*D580Y)#Hht/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory